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张南刚，男，1982年10月生，四川仁寿人，党员，副教授，硕士生导师。2006年6月获武汉大学电子与科学技术工学学士学位。2008年9月至2009年1月在美国加州大学洛杉矶分校(UCLA)医学院做短期交流访问。2012年6月获武汉大学微电子学与固体电子学工学博士学位。2012年9月至今在武汉纺织大学电子与电气工程学院任教。2018年4月受聘于电子科技大学生命科学与技术学院&医学装备研究所任特聘副教授。2019年4月至今任智能微纳医学检验装备及关键技术湖北省工程研究中心和湖北省功能纤维加工及检测工程技术研究中心副主任。主要从事微流控芯片、体外肿瘤检测新技术、医学检测技术与设备、智能可穿戴装备等领域的研究。主持并完成国家自然科学基金-青年项目1项，主持湖北省教育厅重点项目1项，参与国家自然科学基金-重大科研仪器研制专项、湖北省科技厅创新群体、湖北省教育厅优秀中青年创新团队项目各1项，主持企业横向5项，参与企业横向3项，主持和参研各类项目经费累计600余万。近年来在Advanced Materials， ACS Applied Materials & Interfaces， Lab on a Chip， Journal of Translational Medicine等国际学术期刊上发表SCI论文20余篇，授权中国发明专利7项，国际专利（日本）1项。
一、纵向科研项目：
1. “基于微流控芯片的白血病分型FISH检测新技术研究”，湖北省教育厅重点项目，项目主持，4万元，2020.01.01-2021.12.31，在研。
2. “基于纳米纤维材料的循环肿瘤细胞高效捕获与释放研究”，国家自然科学基金-青年项目，项目主持，24万元，项目号：51303140，2014.01.01-2016.12.30，已结题。
3. “基于微流控技术的全自动胎儿有核红细胞分析仪”，国家自然科学基金-重大科研仪器研发专项，项目参与（经费总额：640万元，个人承担45万元），项目号：81527801，2016.01.01-2020.12.30，已结题。
4. “多指标荧光便携检测设备的研发及其在心血管疾病诊断中的应用”，湖北省自然科学基金-创新群体，项目参与，50万元，项目号：2022CFA038，2022.10.01-2025.09.30，在研。
5. “微流控肿瘤检测芯片”，湖北省教育厅优秀中青年创新团队项目，项目参与，20万元，2013.01.01-2016.12.31，已结题。
6. “基于智能物联的动物瘤胃pH值和温度实时检测装置研究”，校基金-特别专项，项目主持，8万元，项目号：校2024571，2024.01.01-2024.12.31，在研。
二、横向企业项目：
1. “光电检测模组定制开发”，企业横向，项目主持，10万元，2022.04.01-2023.03.31，已结题。
2. “显微扫描成像运动平台开发”，企业横向，项目主持，30万元，2022.10.01-2023.09.30，已结题。
3. “直流无刷电机控制板开发”，企业横向，项目主持，5万元，2022.11.01-2023.10.31，已结题。
4. “沉降式制片机运动控制”，企业横向，项目主持，15万元，2022.11.01-2023.10.31，已结题。
5. “全自动液基FISH检测系统”，企业横向，项目参与，280万元，2018.07.06-2019.12.31，已结题。
6. “大通量自动染色机开发”，企业横向，项目参与，7万元，2018.07.01-2018.12.31，已结题。
7. “自动血液骨髓推片机开发”，企业横向，项目参与，15万元，2018.06.11-2018.12.11，已结题。
8. “微型化声表面波检测器研发（一期）”，企业横向，项目主持，3.2万元，2014.11.30-2015.05.30，已结题。
1. An Automated Detection of Influenza Virus based on 3-D Magnetophoretic Separation and Magnetica Label, Shaoli Hong†, Nangang Zhang†, Li Qin, Man Tang, Zhao Ai, Aiju Chen, Kan Liu*, Analyst, 2021,146, 930-936 (二区，IF=3.978) (共同一作)
2. Simultaneous and Automated Detection of Influenza a Virus Hemagglutinin H7 and H9 Based on Magnetism and Size Mediated Microfluidic Chip, Shuibing Wang, Zhao Ai, Zefen Zhang, Man Tang, Nangang Zhang, Fen liu, Gujing Han, Shaoli Hong*, Kan Liu*, Sensors and Actuators B: Chemical, 2020, Volume 308, 127675 (一区Top，IF=7.1)
3. Negative Depletion Mediated Brightfield Circulating Tumor Cell Identification Strategy on Microparticle-Based Microfluidic Chip, Shuibing Wang, Shaoli Hong, Shijia Cai, Jia Lei, Jinyao Chen, Nangang Zhang，Zhao Ai, Kan Liu*, Man Tang*, Journal of Nanobiotechnology, 2020,18(1),70(二区，IF= 6.518)
4. High-performance Multiplex Microvalves Fabrication And Using for Tumor Cells Staining On A Microfluidic Chip, Shaoli Hong, Man Tang, Zhengqi Chen, Zhao Ai, Feng Liu, Shuibing Wang, Nangang Zhang*, Kan Liu*, Biomedical Microdevices, 2019: 21,87 (三区，IF= 2.176) (通讯作者)
5. Simple and Convenient Microfluidic Flow Rate Measurement Based on Microbubble Image Velocimetry, Man Tang, Feng Liu, Jia Lei, Zhao Ai, Shaoli Hong, Nangang Zhang*，Kan Liu*，Microfluid Nanofluid, 2019,23(11),118(三区，IF= 2.489) (通讯作者)
6. Highly Efficient Isolation of Circulating Tumor Cells Based on Multiple Biophysical Properties Using a Simple Wedge-shaped Microfluicdic Device, Luman Qin, Wei Zhou, Shoukun Zhang, Boran Cheng, Shubin Wang, Songzhan Li, Yanqin Yang, Shengxiang Wang, Kan Liu, Nangang Zhang*, IEEE Transactions on Biomedical Engineering, 2019(66), 1536-1541 (二区，IF= 4.424) (通讯作者)
7. Generation of Linear and Parabolic Concentration Gradients by Using a Christmas Tree-shape Microfluidic Network, Qilong Shen, Qiongwei Zhou, Zhigang Lu, Nangang Zhang*, Wuhan University Journal of Natural Sciences, 2018, Vol.23, No.3, 244-250. (通讯作者)
8. A Simple Pyramid-shaped Microchamber towards Highly Efficient Isolation of Circulating Tumor Cells from Breast Cancer Patients, Feng Liu, Shuibing Wang, Zhigang Lu, Yumei Sun, Chaogang Yang, Qiongwei Zhou, Shaoli Hong, Shengxiang Wang, Bin Xiong, Kan Liu, Nangang Zhang*, Biomedical Microdevices, 2018, 20:83. (三区，IF=2.176) (通讯作者)
9. Wedge-shaped Microfluidic Chip for Circulating Tumor Cells Isolation and Its Clinical Significance in Gastric Cancer, Chaogang Yang†, Nangang Zhang†, Shuyi Wang, Dongdong Shi, Chunxiao Zhang, Kan Liu, and Bin Xiong, Journal of Translational Medicine, 2018, 16:139. (二区，IF=4.124) (共同一作)
10. Platelet-Leukocyte Hybrid Membrane-Coated Immunomagnetic Beads for Highly Efficient and Highly Specific Isolation of Circulating Tumor Cells, Lang Rao, Qian-Fang Meng, Qinqin Huang, Zixiang Wang, Guang-Tao Yu, Andrew Li, Weijie Ma, Nangang Zhang, Shi-Shang Guo, Xing-Zhong Zhao, Kan Liu*, Yufeng Yuan*, and Wei Liu*, Advanced Functional Materials, 2018, 1803531. (一区Top，IF=16.836)
11. Enhanced Performance of Multi-dimensional CoS nanoflake/NiO Nanosheet Architecture with Synergetic Effect for Asymmetric Supercapacitor, Yanqin Yang, Songzhan Li, Feng Liu, Jian Wen, Nangang Zhang, Shengxiang Wang, Kan Liu, Nanotechnology, 29(45), 2018. (二区Top，IF=3.551)
12. Highly Efficient Isolation and Release of Circulating Tumor Cells Based on Size-dependent Filtration and Degradable ZnO Nanorods Substrate in a Wedge-shaped Microfluidic Chip, Songzhan Li, Yifan Gao, Xiran Chen, Luman Qin, Boran Cheng, Shubin Wang, Shengxiang Wang, Guangxin Zhao, Kan Liu, Nangang Zhang*, Biomedical Microdevices, 2017, 19(4), 93. (三区，IF=2.176) (通讯作者)
13. PMMA Microfluidic Chip Fabrication Using Laser Ablation and Low Temperature Bonding with OCA Film and LOCA, Kan Liu, Jianzhen Xiang, Zhao Ai, Shoukun Zhang, Yi Fang, Ting Chen, Qiongwei Zhou, Songzhan Li, Shengxiang Wang, Nangang Zhang*, Microsystem Technologies, 2017, 23(6), 1937-1942. (四区，IF=1.737) (通讯作者)
14. Bidirectional Electroluminescence from p-SnO2/i-MgZnO/n-ZnO Heterojunction Light-emitting Diodes, Yanqin Yang, Songzhan Li, Feng Liu, Nangang Zhang, Kan Liu, Shengxiang Wang, Guojia Fang, Journal of Luminescence, 2017,186, 223-228. (二区，IF=3.28)
15. Capture and Release of Cancer Cells by Combining On-Chip Purification and Off-Chip Enzymatic Treatment，Xiaolei Yu†, Bingrui Wang†, Nangang Zhang†, Changqing Yin, Hao Chen, Lingling Zhang, Bo Cai, Zhaobo He, Lang Rao, Wei Liu, Fu-Bing Wang, Shi-Shang Guo, Xing-Zhong Zhao, Acs Applied Materials & Interfaces, 2015, 7(43), 24001-24007. (1区Top，IF=8.758) (共同一作)
16. Self-amplified Piezoelectric Nanogenerator with Enhanced Output Performance: The Synergistic Effect of Micropatterned Polymer Film and Interweaved Silver Nanowires, Chang Liu, Bo Hua, Sujian You, Chenghao Bu, Xiaolei Yu, Zhenhua Yu, Nian Chen, Bo Cai, Huiqin Liu, Shasha Li, Lingling Zhang, Shengxiang Wang, Kan Liu, Nangang Zhang, Wei Liu, Shi-shang Guo*, and Xing-Zhong Zhao, Applied Physics Letters, 2015, 106, 163901. (二区Top，IF=3.597)
17. Self-powered Blue-sensitive Photodetector Based on PEDOT: PSS/SnO2 Microwires Organic/inorganic p-n Heterojunction, Songzhan Li, Shengxiang Wang, Kan Liu, Nangang Zhang, Zhiyou Zhong, Hao Long, Guojia Fang, Applied Physics A, 2015, 119, 1561-1566. (四区，IF=1.81)
18. An Automatic Microfluidic Sample Transfer and Introduction System，Kan Liu, Nan-Gang Zhang, Sheng-Xiang Wang, Yu-Liang Deng, Microfluid Nanofluid (2014) 16:101-108. (三区，IF= 2.489)
19. Electrospun TiO2 Nanofiber-based Cell Capture Assay for Detecting Circulating Tumor Cells from Colorectal and Gastric Cancer Patients, Nangang Zhang, Yuliang Deng, Qidong Tai, Longye Hong, Qinglin Shen, Boran Cheng, Bin Xiong, Hsian-Rong Tseng, Shi-Shang Guo, Kan Liu, Xing-Zhong Zhao, Advanced Materials, 2012, 24, 2756-2760. (一区Top，IF=27.398) (第一作者，内封面文章)
20. Generation of Disk-like Hydrogel Beads for Cell Encapsulation and Manipulation Using a Droplet-based Microfluidic Device, Kan Liu†, Yuliang Deng†, Nangang Zhang†, Sizhe Li，Huijiang Ding, Feng Guo, Wei Liu, Shi-ShangGuo, Xing-Zhong Zhao, Microfluid and Nanofluid, 2012, 13(5), 761-767. (三区，IF= 2.489) (共同一作)
21. An Inverted Fabrication Method Towards A Flexible Dye Sensitized Solar Cell Based on a Free-standing TiO2 Nanowires Membrane, Bolei Chen, Hao Hu, Qidong Tai, Nangang Zhang, Feng Guo, Bobby Sebo, Wei Liu, Jikang Yuan, Jianbo Wang, Xing-Zhong Zhao, Electrochimica Acta, 2012, 59, 581-586. (二区Top，IF=6.215)
22. Rapid Purification of Cell Encapsulated Hydrogel Beads from Oil Phase to Aqueous Phase in a Microfluidic Device, Yuliang Deng†, Nangang Zhang†, Libo Zhao, Xiaolei Yu, Xinghu Ji, Wei Liu, Shi-Shang Guo, Kan Liu, Xing-Zhong Zhao, Lab Chip, 2011, 11, 4117-4121. (一区Top，IF=6.774) (共同一作)
23. Integrated Parallel Microfluidic Device for Simultaneous Preparation of Multiplex Optical-encoded Microbeads with Distinct Quantum Dots Barcodes, Xinghu Ji, Nangang Zhang, Wei Cheng, Feng Guo, Wei Liu, Shishang Guo, Zhike He, Xing-Zhong Zhao, Journal of Materials Chemistry, 2011, 21, 13380-13387. (一区Top，IF= 11.301)
24. Controllable Fission of Droplets and Bubbles by Pneumatic Valve, Hongwei Zhu, Nangang Zhang, Rongxiang He, Shize Li, Shishang Guo, Wei Liu, Xingzhong Zhao, Microfluid Nanofluid, 2011, 10, 1343-1349. (三区，IF= 2.489)
25. A Novel Method for Generation of Amphiphilic PDMS Particles by Selective Modification, Libo Zhao, Sizhe Li, Hao Hu，Zhixiao Guo, Feng Guo, Nangang Zhang, Xinghu Ji, Wei Liu, Kan Liu, Shi-Shang Guo, Xing-Zhong Zhao, Microfluid Nanofluid, 2011, 10, 453-458. (三区，IF= 2.489)
26. A Microfluidic Platform for Systems Pathology: Multiparameter Single-cell Signaling Measurements of Clinical Brain Tumor Specimens, Jing Sun, Michael D. Masterman-Smith, Nicholas A. Graham, Jing Jiao, Jack Mottahedeh, Dan R. Laks, Minori Ohashi, Jason DeJesus, Ken-ichiro Kamei, Ki-Bum Lee, Hao Wang, Zeta T.F. Yu, Yi-Tsung Lu, Shuang Hou, Keyu Li, Max Liu, Nangang Zhang, Shutao Wang, Brigitte Angenieux, Eduard Panosyan, Eric R. Samuels, Jun Park, Dirk Williams, Vera Konkankit, David Nathanson, R. Michael van Dam, Michael E. Phelps, Hong Wu, Linda M. Liau, Paul S. Mischel, Jorge A. Lazareff, Harley I. Kornblum, William H. Yong, Thomas G. Graeber, Hsian-Rong Tseng, Cancer Research, 2010, 70, 6128-6138. (一区Top，IF=9.727)
27. An Integrated Microfluidic Device for Large-Scale In Situ Click Chemistry Screening, Yanju Wang, Wei-Yu Lin, Kan Liu, Rachel J. Lin, Matthias Selke, Hartmuth C. Kolb, Nangang Zhang, Xing-Zhong Zhao, Michael E. Phelps, Clifton K. F. Shen, Kym F. Faull, Hsian-Rong Tseng, Lab Chip, 2009, 9, 2281-2285. (一区Top，IF=6.774)
1. 张南刚, 周琼伟, 刘侃, 方义, 一种阶梯结构的微流控芯片及其制备方法, 发明专利, 2018.9.7, 专利授权号: ZL201510976850.X
2. 张南刚，周琼伟，刘侃, 刘松林, 一种三维结构的细胞捕获与释放芯片及其制备方法, 发明专利，2017.5.31，专利授权号: ZL201510920232.3
3. 李颂战, 高易凡, 刘侃, 张南刚, 刘松林, 氧化锌纳米棒阵列的微粒释放芯片、制备方法及释放方法, 发明专利， 2017.10.17，专利授权号: ZL201510920209.4
4. 刘侃, 汪胜祥, 张南刚, マイクロ流体細胞の捕獲チップ及びの製作方法, 国际(日本)发明专利，2017.6.23，专利授权号: 特许第6163560号
5. 刘威, 刘侃, 张南刚, 国世上, 周鹏飞, 一种利用微流芯片捕获肿瘤细胞的方法, 发明专利, 2015.04.15, 专利授权号: ZL201310359159.8
6. 刘威, 刘侃, 张南刚, 国世上, 周鹏飞, 一种微流芯片的制备方法, 发明专利, 2015.01.14, 专利授权号: ZL201310310907.3
7. 刘威, 刘侃, 张南刚, 国世上, 周鹏飞, 一种能够捕获肿瘤细胞的微流芯片, 发明专利, 2014.11.19, 专利授权号: ZL201310360654.0
8. 刘侃, 汪胜祥, 张南刚, 一种微流体细胞捕获芯片及其制备方法, 发明专利, 2014.06.18, 专利授权号: ZL201210442637.7
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